Most people with type 2 diabetes take medication to manage blood sugar. The most common first medication is metformin.
Patient taps
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Signal · live — no key required
Ask a real health question. Get a real, federally-sourced answer.
This is the live corpus behind Signal — the adaptive health-messaging engine for apps and agents. Every answer is a real, already-public federal fact, list, or tip. Receptivity scoring and the audience-safety verdict come with a free key.
Or try one →
With a free key
The facts are public and free — that's the safety model. The free key unlocks the live cue loop — every cue scored for receptivity and checked safe for its audience. Clinical arc sequencing switches on with a paid stream.
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Receptivity scoring
Every cue returns a receptivity score — when this patient is most likely to act.
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Audience-safety verdict
Every message checked safe for who's receiving it.
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The live cue loop
Create a patient stream, send a response token, get the next federal message — in your app.
See it sequence
One fact is the demo. The arc is the product.
The call above returns one fact. On a paid stream, Signal sequences the whole federal library into a per-episode arc — each message placed by day and phase, checked safe for the patient, and timed to when they are most likely to act. Here is the opening phase of a real clinical arc.
Pick a clinical arc →
Diabetes · Pharma Init
Weight · GLP-1 Init
Heart · Pharma Init
Hypertension · Lifestyle
Quit Smoking
Relapse Prevention
Diabetes · Pharma Init
Starting dose
Metformin is the most commonly prescribed first medication for type 2 diabetes. It comes as pills and a liquid.
Patient taps
That is new to me
Metformin is taken with meals. Doctors usually start with a low dose and raise it gradually every 1 to 2 weeks.
Patient taps
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Common metformin side effects include diarrhea, nausea, gas and changes in taste. Most fade after the first few weeks.
Patient taps
That is new to me
Pair your morning medication with something you already do at the same time. Brushing teeth or starting coffee works well.
Patient taps
I will try that
On metformin, pair the dose with the largest meal of the day. The food cushions early GI side effects.
Patient taps
I will try that
This is a fixed illustrative slice. The live engine picks each next message from the full federal library — sequenced to the arc, timed to receptivity, and checked safe for the patient.
How it scales
From one fact to the full engine
1
Ask
GET /v1/public/health-fact?q=…
One GET call, no key. Returns a real, federally-sourced fact, list, or tip — exactly what you are using right now.
→
2
Get a free key
Display modeA sandbox key in about five minutes — no PHI, no BAA. Render real federal messages in your own app.
→
3
Sequence
POST /v1/signal/streams/:id/cue
Send a patient's context. Get the next message — receptivity-scored, audience-safety-checked. Paid streams draw from the full federal library, sequenced to a clinical arc.
Quickstart
Five-minute integration
$ curl "https://api.uphealth.us/v1/public/health-fact?q=cholesterol" { "fact": { "kind": "fact", "body": "Having high blood cholesterol puts you at risk for heart disease, the leading cause of death in the U.S.", "agency": "NHLBI", "source_url": "https://www.nhlbi.nih.gov/health/blood-cholesterol", "uphealth_url": "https://uphealth.me/health/cholesterol-basics" }, "topic": "Cholesterol Basics", "disclaimer": "General health information from federal public-domain sources — not medical advice…", "attribution": "Source: NHLBI via Uphealth", "upgrade": { "signup_url": "https://uphealth.us/signup" } }
Call it from the OpenAI and Claude agent SDKs, the MCP server, or plain HTTP.
Or paste
https://mcp.uphealth.us/mcp
into Claude or ChatGPT as a custom connector —
MCP quickstart →.
Evaluating for your org? Your assistant can read the samples, check the sourcing, and write the memo — evaluate with your assistant →.
Why a key, not a pipe
“We’ll just use Twilio.”
Twilio sends. Signal decides what to send, whether it is safe for this person, and what comes next.
“The content is free.”
It is — we source from the same CDC and NIH pages. You pay for the sequencing, the audience-safety verdict, and not maintaining freshness and linting yourself.
Developer sign-up
One key. The whole engine.
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