GLP-1 medications work best when combined with a lifestyle program of diet and physical activity.
Patient taps
That is new to me
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Result for
weight loss
live
One real keyless call
GET /v1/public/health-fact?q=weight loss
CDC
Calories, Fruits & Vegetables
federal source · public domain
Weight loss happens when the body uses more calories than it takes in.
General health information from federal public-domain sources — not medical advice, diagnosis, or treatment.
That was one real, public federal answer — and it's free. Receptivity scoring and the audience-safety verdict on every cue come with a free key.
With a free key
The facts are public and free — that's the safety model. The free key unlocks the live cue loop — every cue scored for receptivity and checked safe for its audience. Clinical arc sequencing switches on with a paid stream.
free key
Receptivity scoring
Every cue returns a receptivity score — when this patient is most likely to act.
free key
Audience-safety verdict
Every message checked safe for who's receiving it.
free key
The live cue loop
Create a patient stream, send a response token, get the next federal message — in your app.
See it sequence
One fact is the demo. The arc is the product.
The call above returns one fact. On a paid stream, Signal sequences the whole federal library into a per-episode arc — each message placed by day and phase, checked safe for the patient, and timed to when they are most likely to act. Here is the opening phase of a real clinical arc.
Pick a clinical arc →
Diabetes · Pharma Init
Weight · GLP-1 Init
Heart · Pharma Init
Hypertension · Lifestyle
Quit Smoking
Relapse Prevention
Weight · GLP-1 Init
Starting dose
GLP-1 medications work alongside a lifestyle program of diet and physical activity.
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The most common GLP-1 side effects are stomach-related: nausea, vomiting, diarrhea or constipation.
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GLP-1 medications also slow the emptying of the stomach so food stays longer after meals.
Patient taps
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Smaller meals work better than large meals when food stays in the stomach longer.
Patient taps
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Side effects often improve as your body adjusts over the first few weeks.
Patient taps
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This is a fixed illustrative slice. The live engine picks each next message from the full federal library — sequenced to the arc, timed to receptivity, and checked safe for the patient.
How it scales
From one fact to the full engine
1
Ask
GET /v1/public/health-fact?q=…
One GET call, no key. Returns a real, federally-sourced fact, list, or tip — exactly what you are using right now.
→
2
Get a free key
Display modeA sandbox key in about five minutes — no PHI, no BAA. Render real federal messages in your own app.
→
3
Sequence
POST /v1/signal/streams/:id/cue
Send a patient's context. Get the next message — receptivity-scored, audience-safety-checked. Paid streams draw from the full federal library, sequenced to a clinical arc.
Quickstart
Five-minute integration
$ curl "https://api.uphealth.us/v1/public/health-fact?q=cholesterol" { "fact": { "kind": "fact", "body": "Having high blood cholesterol puts you at risk for heart disease, the leading cause of death in the U.S.", "agency": "NHLBI", "source_url": "https://www.nhlbi.nih.gov/health/blood-cholesterol", "uphealth_url": "https://uphealth.me/health/cholesterol-basics" }, "topic": "Cholesterol Basics", "disclaimer": "General health information from federal public-domain sources — not medical advice…", "attribution": "Source: NHLBI via Uphealth", "upgrade": { "signup_url": "https://uphealth.us/signup" } }
Call it from the OpenAI and Claude agent SDKs, the MCP server, or plain HTTP.
Or paste
https://mcp.uphealth.us/mcp
into Claude or ChatGPT as a custom connector —
MCP quickstart →.
Evaluating for your org? Your assistant can read the samples, check the sourcing, and write the memo — evaluate with your assistant →.
Why a key, not a pipe
“We’ll just use Twilio.”
Twilio sends. Signal decides what to send, whether it is safe for this person, and what comes next.
“The content is free.”
It is — we source from the same CDC and NIH pages. You pay for the sequencing, the audience-safety verdict, and not maintaining freshness and linting yourself.
Developer sign-up
One key. The whole engine.
Building something for real? We pair with a few founding partners →